While in the Pause Menu: Left, Left, Right, Left, Right, Up, Start. - One Hit Kills
At forge or beast's equipment screen: Up, Up, Up, Down, Right, Right, Start - 100,000 Techbits
Character selection at Xtraction point input: Left, Right, Left, Right, Down, Up, Start. - A skill point added to abilities without points already on it.
At team management screen: Right, Left, Left, Right, Up, Up, Up, Start. - All Characters
In the Review Menu: Right, Left, Left, Right, Up, Up, Right, Start. - All comic books
In the Danger Room: Right, Right, Left, Left, Up, Down, Up Down, Start. - All Danger Room Courses
While in the Pause Menu: Down, Up, Down, Up, Right, Down, Right, Left, Start. - God Mode
At team management screen: Up, Down, Up, Down, Left, Up, Left, Right, Start. - Level 99 Characters
In the pause menu: Up, Up, Up, Down, Up, Down, Start. - Super Speed
In the pause menu: Left, Down, Right, Down, Up, Up, Down, Up Start. - Unlimited XTreme Power
At the team management screen: Down, Up, Left, Right, Up, Up, Start. - Unlock All Character Skins.
In the review menu: Left, Right, Left, Right, Up, Up, Down, Start. - Unlock all concept art
In the Review Menu: Left, Right, Right, Left, Down, Down, Left, Start. - Unlock all cinematics
At team management screen: Left, Right, Left, Right, Down, Up, Start. - Unlock all skills
X-Man - Find the playable comic mission 'Age Of Apocalypse' in the 1st act of the game.
Cable - Beat the "X-cutioner's Song" playable comic mission.
Cannonball - Beat the "Brood: Day of Wrath" playable comic mission.
Dark Phoenix - Beat the game on any difficulty level.
Deadpool - Beat the game on any difficulty level.
Professor X - Beat all the Danger Room missions.
Iron Man - Collect one of the four homing beacons in each act, then go to the Home location. Enter the portal and fight until you reach one of Iron Man's items.
Use the teams to unlock the specific bonuses of their grouping:
Age of Apocalypse: +100% attack rating - Any 4 heroes with AoA skins
Agile Warriors: +5% XP - Nightcrawler, Sunfire, Toad, Deadpool
Brotherhood of Evil: +5% Experience - Juggernaut, Magneto, Scarlet Witch, Toad
Bruiser Brigade: 20 Energy gained per knockout - Juggernaut, Colossus, Wolverine, Rogue
Dark Past Team: 5% damage inflicted to health - Deadpool, Rogue, Wolverine, and Gambit
Double Date: 20 Health per KO - Cyclops, Jean Grey, Gambit, Rogue
Energy Corps: +5% damage - Gambit, Bishop, Cyclops, Iron Man
Family Affair: +5 health regeneration - Magneto, Professor X, Scarlet Witch, Juggernaut
Femme Fatale: 5% damage inflicted goes to health - Storm, Scarlet Witch, Rogue, Jean Grey
Forces of Nature: +10 to all resistances - Storm, Iceman, Sunfire, Magneto
Heavy Metal: +10 to all Stats - Colossus, Juggernaut, Iron Man, Magneto
New Avengers: +15% max health - Iron Man, Scarlet Witch, Wolverine, Bishop
New X-Men: +15% max health - Nightclawler, Storm, Colossus, Wolverine, Sunfire, Bishop
Old School: +15% Max Energy - Cyclops, Jean Grey, Iceman, Magneto, Toad, Professor X
Raven Knights: +60% techbit drops - Iceman, Professor X, Iron Man, Deadpool
Special Ops: +5% damage - Bishop, Deadpool, Nightcrawler, Gambit
Complete Act I - Snow Iceman, Brown & Gold Wolverine, Original and 70's Cyclops, Original and 70's Jean, 70's Nightcrawler, Colossus, & Storm
Complete Act II - Age of Apocalypse Costumes & original Scarlet Witch costume
Complete Act III - Civilian costume for Storm, Cyclops, & Wolverine